DNA Structure Modulates the Oligomerization Properties of the AAV Initiator Protein Rep68

Rep68 is a multifunctional protein of the adeno-associated virus (AAV), a parvovirus that is mostly known for its promise as a gene therapy vector. In addition to its role as initiator in viral DNA replication, Rep68 is essential for site-specific integration of the AAV genome into human chromosome...

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Detalles Bibliográficos
Autores principales: Mansilla-Soto, Jorge, Yoon-Robarts, Miran, Rice, William J., Arya, Shailee, Escalante, Carlos R., Linden, R. Michael
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2702170/
https://www.ncbi.nlm.nih.gov/pubmed/19593381
http://dx.doi.org/10.1371/journal.ppat.1000513

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2702170/
https://www.ncbi.nlm.nih.gov/pubmed/19593381
http://dx.doi.org/10.1371/journal.ppat.1000513

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