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Heme oxygenase-1 and its metabolites affect pancreatic tumor growth in vivo

BACKGROUND: Pancreatic cancer (PaCa) is a fatal human cancer due to its exceptional resistance to all current anticancer therapies. The cytoprotective enzyme heme oxygenase-1 (HO-1) is significantly overexpressed in PaCa and seems to play an important role in cancer resistance to anticancer treatmen...

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Detalles Bibliográficos
Autores principales: Nuhn, Philipp, Künzli, Beat M, Hennig, René, Mitkus, Tomas, Ramanauskas, Tadas, Nobiling, Rainer, Meuer, Stefan C, Friess, Helmut, Berberat, Pascal O
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2702301/
https://www.ncbi.nlm.nih.gov/pubmed/19508729
http://dx.doi.org/10.1186/1476-4598-8-37