Comparative study on the effect of human BST-2/Tetherin on HIV-1 release in cells of various species

In this study, we first demonstrate that endogenous hBST-2 is predominantly expressed on the plasma membrane of a human T cell line, MT-4 cells, and that Vpu-deficient HIV-1 was less efficiently released than wild-type HIV-1 from MT-4 cells. In addition, surface hBST-2 was rapidly down-regulated in...

Descripción completa

Detalles Bibliográficos
Autores principales: Sato, Kei, Yamamoto, Seiji P, Misawa, Naoko, Yoshida, Takeshi, Miyazawa, Takayuki, Koyanagi, Yoshio
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2702332/
https://www.ncbi.nlm.nih.gov/pubmed/19490609
http://dx.doi.org/10.1186/1742-4690-6-53

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2702332/
https://www.ncbi.nlm.nih.gov/pubmed/19490609
http://dx.doi.org/10.1186/1742-4690-6-53

Ejemplares similares