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Differential baseline and response profile to IFN-γ gene transduction of IL-6/IL-6 receptor-α secretion discriminate primary tumors versus bone marrow metastases of nasopharyngeal carcinomas in culture

BACKGROUND: Understanding of immunobiology of bone marrow metastases (designated BM-NPC) versus primary tumors (P-NPC) of the nasopharynx is far from complete. The aim of this study was to determine if there would be differences between cultured P-NPCs and BM-NPCs with respect to (i) constitutive IL...

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Detalles Bibliográficos
Autores principales: Chou, Andy Shau-Bin, Wang, Hsin-Yi, Chen, Hung-Chang, Tsai, Ming-Hsiu, Chuang, Cheng-Keng, Liao, Shuen-Kuei
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2702388/
https://www.ncbi.nlm.nih.gov/pubmed/19497133
http://dx.doi.org/10.1186/1471-2407-9-169