Fast simultaneous detection of K-RAS mutations in colorectal cancer

BACKGROUND: RAS genes acquire the most common somatic gain-of-function mutations in human cancer, and almost all of these mutations are located at codons 12, 13, 61, and 146. METHODS: We present a method for detecting these K-RAS hotspot mutations in 228 cases of colorectal cancer. The protocol is b...

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Detalles Bibliográficos
Autores principales: Chang, Ya-Sian, Yeh, Kun-Tu, Chang, Tien-Jye, Chai, Connie, Lu, Hsiu-Chin, Hsu, Nicholas C, Chang, Jan-Gowth
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Technical Advance
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2702390/
https://www.ncbi.nlm.nih.gov/pubmed/19515263
http://dx.doi.org/10.1186/1471-2407-9-179

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2702390/
https://www.ncbi.nlm.nih.gov/pubmed/19515263
http://dx.doi.org/10.1186/1471-2407-9-179

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