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Fast simultaneous detection of K-RAS mutations in colorectal cancer
BACKGROUND: RAS genes acquire the most common somatic gain-of-function mutations in human cancer, and almost all of these mutations are located at codons 12, 13, 61, and 146. METHODS: We present a method for detecting these K-RAS hotspot mutations in 228 cases of colorectal cancer. The protocol is b...
| Autores principales: | , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2702390/ https://www.ncbi.nlm.nih.gov/pubmed/19515263 http://dx.doi.org/10.1186/1471-2407-9-179 |