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A comparative study of methylglyoxal metabolism in trypanosomatids

The glyoxalase system, comprising the metalloenzymes glyoxalase I (GLO1) and glyoxalase II (GLO2), is an almost universal metabolic pathway involved in the detoxification of the glycolytic byproduct methylglyoxal to d-lactate. In contrast to the situation with the trypanosomatid parasites Leishmania...

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Detalles Bibliográficos
Autores principales: Greig, Neil, Wyllie, Susan, Patterson, Stephen, Fairlamb, Alan H
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2702497/
https://www.ncbi.nlm.nih.gov/pubmed/19076214
http://dx.doi.org/10.1111/j.1742-4658.2008.06788.x