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The Schizosaccharomyces pombe Checkpoint Kinases Chk1 and Cds1 Are Important for Cell Survival in Response to Cisplatin

BACKGROUND: DNA damage checkpoints insure that the integrity of genomic DNA is faithfully maintained throughout the eukaryotic cell cycle. In the presence of damaged DNA, checkpoints are triggered to delay cell cycle progression to allow for DNA repair. In fission yeast, the kinases Chk1 and Cds1 ar...

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Detalles Bibliográficos
Autores principales: Paparatto, Domenica, Fletcher, Dane, Piwowar, Karen, Baldino, Kimberly, Morel, Charlotte, Dunaway, Stephen
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2702685/
https://www.ncbi.nlm.nih.gov/pubmed/19587778
http://dx.doi.org/10.1371/journal.pone.0006181