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Clustering of IP(3) receptors by IP(3) retunes their regulation by IP(3) and Ca(2+)

The versatility of Ca(2+) signals derives from their spatio-temporal organization1,2. For Ca(2+) signals initiated by inositol trisphosphate (IP(3)) this requires local interactions between IP(3) receptors (IP(3)R)3,4 mediated by their rapid stimulation and slower inhibition4 by cytosolic Ca(2+). Th...

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Detalles Bibliográficos
Autores principales: Taufiq-Ur-Rahman, Skupin, Alexander, Falcke, Martin, Taylor, Colin W.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2702691/
https://www.ncbi.nlm.nih.gov/pubmed/19348050
http://dx.doi.org/10.1038/nature07763