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Clustering of IP(3) receptors by IP(3) retunes their regulation by IP(3) and Ca(2+)
The versatility of Ca(2+) signals derives from their spatio-temporal organization1,2. For Ca(2+) signals initiated by inositol trisphosphate (IP(3)) this requires local interactions between IP(3) receptors (IP(3)R)3,4 mediated by their rapid stimulation and slower inhibition4 by cytosolic Ca(2+). Th...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2702691/ https://www.ncbi.nlm.nih.gov/pubmed/19348050 http://dx.doi.org/10.1038/nature07763 |