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Reduced Viability, Fertility and Fecundity in Mice Lacking the Cajal Body Marker Protein, Coilin
BACKGROUND: Coilin is the signature protein of the Cajal body, a conserved nuclear organelle involved in multiple aspects of small ribonucleoprotein (RNP) biogenesis. Coilin is required for Cajal body homeostasis in both plants and animals. Mice lacking coilin are viable when the mutation is crossed...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
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Public Library of Science
2009
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2702818/ https://www.ncbi.nlm.nih.gov/pubmed/19587784 http://dx.doi.org/10.1371/journal.pone.0006171 |