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Reduced Viability, Fertility and Fecundity in Mice Lacking the Cajal Body Marker Protein, Coilin

BACKGROUND: Coilin is the signature protein of the Cajal body, a conserved nuclear organelle involved in multiple aspects of small ribonucleoprotein (RNP) biogenesis. Coilin is required for Cajal body homeostasis in both plants and animals. Mice lacking coilin are viable when the mutation is crossed...

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Detalles Bibliográficos
Autores principales: Walker, Michael P., Tian, Liping, Matera, A. Gregory
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2702818/
https://www.ncbi.nlm.nih.gov/pubmed/19587784
http://dx.doi.org/10.1371/journal.pone.0006171