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Evidence for the Concerted Evolution between Short Linear Protein Motifs and Their Flanking Regions

BACKGROUND: Linear motifs are short modules of protein sequences that play a crucial role in mediating and regulating many protein–protein interactions. The function of linear motifs strongly depends on the context, e.g. functional instances mainly occur inside flexible regions that are accessible f...

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Detalles Bibliográficos
Autores principales: Chica, Claudia, Diella, Francesca, Gibson, Toby J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2702822/
https://www.ncbi.nlm.nih.gov/pubmed/19584925
http://dx.doi.org/10.1371/journal.pone.0006052