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The anticancer activity of lytic peptides is inhibited by heparan sulfate on the surface of the tumor cells
BACKGROUND: Cationic antimicrobial peptides (CAPs) with antitumor activity constitute a promising group of novel anticancer agents. These peptides induce lysis of cancer cells through interactions with the plasma membrane. It is not known which cancer cell membrane components influence their suscept...
Autores principales: | Fadnes, Bodil, Rekdal, Øystein, Uhlin-Hansen, Lars |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2703650/ https://www.ncbi.nlm.nih.gov/pubmed/19527490 http://dx.doi.org/10.1186/1471-2407-9-183 |
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