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Promoter Methylation in the Genesis of Gastrointestinal Cancer

Colorectal cancers (CRC)-and probably all cancers-are caused by alterations in genes. This includes activation of oncogenes and inactivation of tumor suppressor genes (TSGs). There are many ways to achieve these alterations. Oncogenes are frequently activated by point mutation, gene amplification, o...

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Detalles Bibliográficos
Autores principales: Boland, Clement Richard, Shin, Sung Kwan, Goel, Ajay
Formato: Texto
Lenguaje:English
Publicado: Yonsei University College of Medicine 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2703751/
https://www.ncbi.nlm.nih.gov/pubmed/19568590
http://dx.doi.org/10.3349/ymj.2009.50.3.309