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Insulin Stimulates Adipogenesis through the Akt-TSC2-mTORC1 Pathway

BACKGROUND: The signaling pathways imposing hormonal control over adipocyte differentiation are poorly understood. While insulin and Akt signaling have been found previously to be essential for adipogenesis, the relative importance of their many downstream branches have not been defined. One direct...

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Detalles Bibliográficos
Autores principales: Zhang, Hui H., Huang, Jingxiang, Düvel, Katrin, Boback, Bernard, Wu, Shulin, Squillace, Rachel M., Wu, Chin-Lee, Manning, Brendan D.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2703782/
https://www.ncbi.nlm.nih.gov/pubmed/19593385
http://dx.doi.org/10.1371/journal.pone.0006189