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Wnt Signaling Is Regulated by Endoplasmic Reticulum Retention
Precise regulation of Wnt signaling is important in many contexts, as in development of the vertebrate forebrain, where excessive or ectopic Wnt signaling leads to severe brain defects. Mutation of the widely expressed oto gene causes loss of the anterior forebrain during mouse embryogenesis. Here w...
Autores principales: | , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2703784/ https://www.ncbi.nlm.nih.gov/pubmed/19593386 http://dx.doi.org/10.1371/journal.pone.0006191 |