CCL2 Accelerates Microglia-Mediated Aβ Oligomer Formation and Progression of Neurocognitive Dysfunction

BACKGROUND: The linkages between neuroinflammation and Alzheimer's disease (AD) pathogenesis are well established. What is not, however, is how specific immune pathways and proteins affect the disease. To this end, we previously demonstrated that transgenic over-expression of CCL2 enhanced micr...

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Detalles Bibliográficos
Autores principales: Kiyota, Tomomi, Yamamoto, Masaru, Xiong, Huangui, Lambert, Mary P., Klein, William L., Gendelman, Howard E., Ransohoff, Richard M., Ikezu, Tsuneya
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2703798/
https://www.ncbi.nlm.nih.gov/pubmed/19593388
http://dx.doi.org/10.1371/journal.pone.0006197

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2703798/
https://www.ncbi.nlm.nih.gov/pubmed/19593388
http://dx.doi.org/10.1371/journal.pone.0006197

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