The Heme Biosynthetic Pathway of the Obligate Wolbachia Endosymbiont of Brugia malayi as a Potential Anti-filarial Drug Target

BACKGROUND: Filarial parasites (e.g., Brugia malayi, Onchocerca volvulus, and Wuchereria bancrofti) are causative agents of lymphatic filariasis and onchocerciasis, which are among the most disabling of neglected tropical diseases. There is an urgent need to develop macro-filaricidal drugs, as curre...

Descripción completa

Detalles Bibliográficos
Autores principales: Wu, Bo, Novelli, Jacopo, Foster, Jeremy, Vaisvila, Romualdas, Conway, Leslie, Ingram, Jessica, Ganatra, Mehul, Rao, Anita U., Hamza, Iqbal, Slatko, Barton
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2703803/
https://www.ncbi.nlm.nih.gov/pubmed/19597542
http://dx.doi.org/10.1371/journal.pntd.0000475

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2703803/
https://www.ncbi.nlm.nih.gov/pubmed/19597542
http://dx.doi.org/10.1371/journal.pntd.0000475

Ejemplares similares