Interference with Hemozoin Formation Represents an Important Mechanism of Schistosomicidal Action of Antimalarial Quinoline Methanols

BACKGROUND: The parasitic trematode Schistosoma mansoni is one of the major causative agents of human schistosomiasis, which afflicts 200 million people worldwide. Praziquantel remains the main drug used for schistosomiasis treatment, and reliance on the single therapy has been prompting the search...

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Detalles Bibliográficos
Autores principales: Corrêa Soares, Juliana B. R., Menezes, Diego, Vannier-Santos, Marcos A., Ferreira-Pereira, Antonio, Almeida, Giulliana T., Venancio, Thiago M., Verjovski-Almeida, Sergio, Zishiri, Vincent K., Kuter, David, Hunter, Roger, Egan, Timothy J., Oliveira, Marcus F.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2703804/
https://www.ncbi.nlm.nih.gov/pubmed/19597543
http://dx.doi.org/10.1371/journal.pntd.0000477

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2703804/
https://www.ncbi.nlm.nih.gov/pubmed/19597543
http://dx.doi.org/10.1371/journal.pntd.0000477

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