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Emerging role of LRRK2 in human neural progenitor cell cycle progression, survival and differentiation

Despite a comprehensive mapping of the Parkinson's disease (PD)-related mRNA and protein leucine-rich repeat kinase 2 (LRRK2) in the mammalian brain, its physiological function in healthy individuals remains enigmatic. Based on its structural features and kinase properties, LRRK2 may interact w...

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Detalles Bibliográficos
Autores principales: Milosevic, Javorina, Schwarz, Sigrid C, Ogunlade, Vera, Meyer, Anne K, Storch, Alexander, Schwarz, Johannes
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2704190/
https://www.ncbi.nlm.nih.gov/pubmed/19523245
http://dx.doi.org/10.1186/1750-1326-4-25