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Structural motifs recurring in different folds recognize the same ligand fragments

BACKGROUND: The structural analysis of protein ligand binding sites can provide information relevant for assigning functions to unknown proteins, to guide the drug discovery process and to infer relations among distant protein folds. Previous approaches to the comparative analysis of binding pockets...

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Detalles Bibliográficos
Autores principales: Ausiello, Gabriele, Gherardini, Pier Federico, Gatti, Elena, Incani, Ottaviano, Helmer-Citterich, Manuela
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2704211/
https://www.ncbi.nlm.nih.gov/pubmed/19527512
http://dx.doi.org/10.1186/1471-2105-10-182