Determination of quantitative and site-specific DNA methylation of perforin by pyrosequencing

BACKGROUND: Differential expression of perforin (PRF1), a gene with a pivotal role in immune surveillance, can be attributed to differential methylation of CpG sites in its promoter region. A reproducible method for quantitative and CpG site-specific determination of perforin methylation is required...

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Detalles Bibliográficos
Autores principales: Narasimhan, Supraja, Falkenberg, Virginia R, Khin, Maung M, Rajeevan, Mangalathu S
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Technical Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2704226/
https://www.ncbi.nlm.nih.gov/pubmed/19523225
http://dx.doi.org/10.1186/1756-0500-2-104

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2704226/
https://www.ncbi.nlm.nih.gov/pubmed/19523225
http://dx.doi.org/10.1186/1756-0500-2-104

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