Catalytically impaired hMYH and NEIL1 mutant proteins identified in patients with primary sclerosing cholangitis and cholangiocarcinoma

The human hMYH and NEIL1 genes encode DNA glycosylases involved in repair of oxidative base damage and mutations in these genes are associated with certain cancers. Primary sclerosing cholangitis (PSC), a chronic cholestatic liver disease characterized by inflammatory destruction of the biliary tree...

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Detalles Bibliográficos
Autores principales: Forsbring, Monika, Vik, Erik S., Dalhus, Bjørn, Karlsen, Tom H., Bergquist, Annika, Schrumpf, Erik, Bjørås, Magnar, Boberg, Kirsten M., Alseth, Ingrun
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2704287/
https://www.ncbi.nlm.nih.gov/pubmed/19443904
http://dx.doi.org/10.1093/carcin/bgp118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2704287/
https://www.ncbi.nlm.nih.gov/pubmed/19443904
http://dx.doi.org/10.1093/carcin/bgp118

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