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Olfactory behavior and physiology are disrupted in prion protein knockout mice
The prion protein PrP(C) is infamous for its role in disease, yet its normal physiological function remains unknown. Here we report a novel behavioral phenotype of PrP(−/−) mice in an odor-guided task. This phenotype is manifest in three PrP knockout lines on different genetic backgrounds, strong ev...
| Autores principales: | , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2704296/ https://www.ncbi.nlm.nih.gov/pubmed/19098904 http://dx.doi.org/10.1038/nn.2238 |