Exploration of the One-Bead One-Compound Methodology for the Design of Prolyl Oligopeptidase Substrates

Here we describe the design, synthesis and evaluation of the first solid-phase substrates for prolyl oligopeptidase (POP), a cytosolic serine peptidase associated with schizophrenia, bipolar affective disorder and related neuropsychiatric disorders. This study seeks to contribute to the future desig...

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Detalles Bibliográficos
Autores principales: Comellas, Gemma, Kaczmarska, Zusanna, Tarragó, Teresa, Teixidó, Meritxell, Giralt, Ernest
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2704865/
https://www.ncbi.nlm.nih.gov/pubmed/19593439
http://dx.doi.org/10.1371/journal.pone.0006222

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2704865/
https://www.ncbi.nlm.nih.gov/pubmed/19593439
http://dx.doi.org/10.1371/journal.pone.0006222

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