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PoreWalker: A Novel Tool for the Identification and Characterization of Channels in Transmembrane Proteins from Their Three-Dimensional Structure

Transmembrane channel proteins play pivotal roles in maintaining the homeostasis and responsiveness of cells and the cross-membrane electrochemical gradient by mediating the transport of ions and molecules through biological membranes. Therefore, computational methods which, given a set of 3D coordi...

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Detalles Bibliográficos
Autores principales: Pellegrini-Calace, Marialuisa, Maiwald, Tim, Thornton, Janet M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2704872/
https://www.ncbi.nlm.nih.gov/pubmed/19609355
http://dx.doi.org/10.1371/journal.pcbi.1000440