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Ryanodine receptor-mediated arrhythmias and sudden cardiac death
The cardiac ryanodine receptor-Ca(2+) release channel (RyR2) is an essential sarcoplasmic reticulum (SR) transmembrane protein that plays a central role in excitation–contraction coupling (ECC) in cardiomyocytes. Aberrant spontaneous, diastolic Ca(2+) leak from the SR due to dysfunctional RyR2 contr...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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Pergamon Press
2009
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2704947/ https://www.ncbi.nlm.nih.gov/pubmed/19345240 http://dx.doi.org/10.1016/j.pharmthera.2009.03.006 |