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Expression of the Bcl-2 Protein BAD Promotes Prostate Cancer Growth

BAD, a pro-apoptotic protein of the Bcl-2 family, has recently been identified as an integrator of several anti-apoptotic signaling pathways in prostate cancer cells. Thus, activation of EGFR, GPCRs or PI3K pathway leads to BAD phosphorylation and inhibition of apoptosis. Increased levels of BAD in...

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Detalles Bibliográficos
Autores principales: Smith, Adrienne J., Karpova, Yelena, D'Agostino, Ralph, Willingham, Mark, Kulik, George
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2704953/
https://www.ncbi.nlm.nih.gov/pubmed/19593445
http://dx.doi.org/10.1371/journal.pone.0006224