Modeling the Repertoire of True Tumor-Specific MHC I Epitopes in a Human Tumor

DNA replication has a finite measurable error rate, net of repair, in all cells. Clonal proliferation of cancer cells leads therefore to accumulation of random mutations. A proportion of these mutational events can create new immunogenic epitopes that, if processed and presented by an MHC allele, ma...

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Detalles Bibliográficos
Autores principales: Srivastava, Nisheeth, Srivastava, Pramod K.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2704956/
https://www.ncbi.nlm.nih.gov/pubmed/19593447
http://dx.doi.org/10.1371/journal.pone.0006094

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2704956/
https://www.ncbi.nlm.nih.gov/pubmed/19593447
http://dx.doi.org/10.1371/journal.pone.0006094

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