Synthesis and Bronchodilator Studies of Some Novel 6-Alkyl/Aryl-1,2,4-Triazino[4,3-c]Quinazolines

A series of alkyl- and aryl-1,2,4-triazino[4,3-c]quinazolines (5a-h and 8a-h) were synthesized and characterized. The title compounds were evaluated for their in vivo bronchodilator activity on guinea pigs. All the test compounds exhibited good protection against histamine-induced bronchospasm. The...

Descripción completa

Detalles Bibliográficos
Autores principales: Kombu, Rajan Subramanian, Mailavaram, Raghu Prasad, Devalapally, Harikrishna, Chinnappa, Prabhakar Marsanapalli, Devarakonda, Rama Krishna, Akkinepally, Raghu Ram Rao
Formato: Texto
Lenguaje:English
Publicado: Bentham Open 2008
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2705134/
https://www.ncbi.nlm.nih.gov/pubmed/19662150
http://dx.doi.org/10.2174/1874104500802010101

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2705134/
https://www.ncbi.nlm.nih.gov/pubmed/19662150
http://dx.doi.org/10.2174/1874104500802010101

Ejemplares similares