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Synthesis and Bronchodilator Studies of Some Novel 6-Alkyl/Aryl-1,2,4-Triazino[4,3-c]Quinazolines

A series of alkyl- and aryl-1,2,4-triazino[4,3-c]quinazolines (5a-h and 8a-h) were synthesized and characterized. The title compounds were evaluated for their in vivo bronchodilator activity on guinea pigs. All the test compounds exhibited good protection against histamine-induced bronchospasm. The...

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Detalles Bibliográficos
Autores principales:	Kombu, Rajan Subramanian, Mailavaram, Raghu Prasad, Devalapally, Harikrishna, Chinnappa, Prabhakar Marsanapalli, Devarakonda, Rama Krishna, Akkinepally, Raghu Ram Rao
Formato:	Texto
Lenguaje:	English
Publicado:	Bentham Open 2008
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2705134/ https://www.ncbi.nlm.nih.gov/pubmed/19662150 http://dx.doi.org/10.2174/1874104500802010101

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