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Base Flipping in Tn10 Transposition: An Active Flip and Capture Mechanism
The bacterial Tn5 and Tn10 transposases have a single active site that cuts both strands of DNA at their respective transposon ends. This is achieved using a hairpin intermediate that requires the DNA to change conformation during the reaction. In Tn5 these changes are controlled in part by a flippe...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2705183/ https://www.ncbi.nlm.nih.gov/pubmed/19593448 http://dx.doi.org/10.1371/journal.pone.0006201 |