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Staphylococcal Enterotoxin A Induces Small Clusters of HLA-DR1 on B Cells

The superantigen SEA causes non-specific hyperactivation of T and B cells at low concentrations. Studies of mutants or soluble proteins suggest SEA is bivalent for its ligand, MHC class II. However, the interaction between these molecules on intact cells is unknown. On primary mouse B cells expressi...

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Detalles Bibliográficos
Autores principales: Narayan, Kedar, Perkins, Edward M., Murphy, Gavin E., Dalai, Sarat K., Edidin, Michael, Subramaniam, Sriram, Sadegh-Nasseri, Scheherazade
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2705189/
https://www.ncbi.nlm.nih.gov/pubmed/19587800
http://dx.doi.org/10.1371/journal.pone.0006188