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Fast and accurate short read alignment with Burrows–Wheeler transform

Motivation: The enormous amount of short reads generated by the new DNA sequencing technologies call for the development of fast and accurate read alignment programs. A first generation of hash table-based methods has been developed, including MAQ, which is accurate, feature rich and fast enough to...

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Detalles Bibliográficos
Autores principales: Li, Heng, Durbin, Richard
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2705234/
https://www.ncbi.nlm.nih.gov/pubmed/19451168
http://dx.doi.org/10.1093/bioinformatics/btp324