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Seeing the forest for the trees: using the Gene Ontology to restructure hierarchical clustering

Motivation: There is a growing interest in improving the cluster analysis of expression data by incorporating into it prior knowledge, such as the Gene Ontology (GO) annotations of genes, in order to improve the biological relevance of the clusters that are subjected to subsequent scrutiny. The stru...

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Detalles Bibliográficos
Autores principales: Dotan-Cohen, Dikla, Kasif, Simon, Melkman, Avraham A.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2705235/
https://www.ncbi.nlm.nih.gov/pubmed/19497934
http://dx.doi.org/10.1093/bioinformatics/btp327