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Seeing the forest for the trees: using the Gene Ontology to restructure hierarchical clustering
Motivation: There is a growing interest in improving the cluster analysis of expression data by incorporating into it prior knowledge, such as the Gene Ontology (GO) annotations of genes, in order to improve the biological relevance of the clusters that are subjected to subsequent scrutiny. The stru...
Autores principales: | Dotan-Cohen, Dikla, Kasif, Simon, Melkman, Avraham A. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2705235/ https://www.ncbi.nlm.nih.gov/pubmed/19497934 http://dx.doi.org/10.1093/bioinformatics/btp327 |
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