Production, crystallization and preliminary crystallographic analysis of an exosite-containing fragment of human von Willebrand factor-cleaving proteinase ADAMTS13

ADAMTS13 is a reprolysin-type metalloproteinase belonging to the ADAMTS (a disintegrin and metalloproteinase with thrombospondin type 1 motif) family. It specifically cleaves plasma von Willebrand factor (VWF) and regulates platelet adhesion and aggregation. ADAMTS13 is a multi-domain enzyme. In add...

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Detalles Bibliográficos
Autores principales: Akiyama, Masashi, Takeda, Soichi, Kokame, Koichi, Takagi, Junichi, Miyata, Toshiyuki
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2009
Materias:
Crystallization Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2705650/
https://www.ncbi.nlm.nih.gov/pubmed/19574655
http://dx.doi.org/10.1107/S1744309109023410

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2705650/
https://www.ncbi.nlm.nih.gov/pubmed/19574655
http://dx.doi.org/10.1107/S1744309109023410

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