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Elongation factor eEF1B modulates functions of the release factors eRF1 and eRF3 and the efficiency of translation termination in yeast

BACKGROUND: Termination of translation in eukaryotes is controlled by two interacting polypeptide chain release factors, eRF1 and eRF3. While eRF1 recognizes nonsense codons, eRF3 facilitates polypeptide chain release from the ribosome in a GTP-dependent manner. Besides termination, both release fac...

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Detalles Bibliográficos
Autores principales: Valouev, Igor A, Fominov, Gleb V, Sokolova, Elizaveta E, Smirnov, Vladimir N, Ter-Avanesyan, Michael D
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2705663/
https://www.ncbi.nlm.nih.gov/pubmed/19545407
http://dx.doi.org/10.1186/1471-2199-10-60