A Novel and Efficient Gene Transfer Strategy Reduces Glial Reactivity and Improves Neuronal Survival and Axonal Growth In Vitro

BACKGROUND: The lack of axonal regeneration in the central nervous system is attributed among other factors to the formation of a glial scar. This cellular structure is mainly composed of reactive astrocytes that overexpress two intermediate filament proteins, the glial fibrillary acidic protein (GF...

Descripción completa

Detalles Bibliográficos
Autores principales: Desclaux, Mathieu, Teigell, Marisa, Amar, Lahouari, Vogel, Roland, Gimenez y Ribotta, Minerva, Privat, Alain, Mallet, Jacques
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2705675/
https://www.ncbi.nlm.nih.gov/pubmed/19597552
http://dx.doi.org/10.1371/journal.pone.0006227

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2705675/
https://www.ncbi.nlm.nih.gov/pubmed/19597552
http://dx.doi.org/10.1371/journal.pone.0006227

Ejemplares similares