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A Comprehensive Analysis of the Structure-Function Relationship in Proteins Based on Local Structure Similarity
BACKGROUND: Sequence similarity to characterized proteins provides testable functional hypotheses for less than 50% of the proteins identified by genome sequencing projects. With structural genomics it is believed that structural similarities may give functional hypotheses for many of the remaining...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2705683/ https://www.ncbi.nlm.nih.gov/pubmed/19603073 http://dx.doi.org/10.1371/journal.pone.0006266 |