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Lipid Reorganization Induced by Shiga Toxin Clustering on Planar Membranes

The homopentameric B-subunit of bacterial protein Shiga toxin (STxB) binds to the glycolipid Gb(3) in plasma membranes, which is the initial step for entering cells by a clathrin-independent mechanism. It has been suggested that protein clustering and lipid reorganization determine toxin uptake into...

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Detalles Bibliográficos
Autores principales: Windschiegl, Barbara, Orth, Alexander, Römer, Winfried, Berland, Ludwig, Stechmann, Bahne, Bassereau, Patricia, Johannes, Ludger, Steinem, Claudia
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2705791/
https://www.ncbi.nlm.nih.gov/pubmed/19606209
http://dx.doi.org/10.1371/journal.pone.0006238