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Synergy between Proteasome Inhibitors and Imatinib Mesylate in Chronic Myeloid Leukemia
BACKGROUND: Resistance developed by leukemic cells, unsatisfactory efficacy on patients with chronic myeloid leukemia (CML) at accelerated and blastic phases, and potential cardiotoxity, have been limitations for imatinib mesylate (IM) in treating CML. Whether low dose IM in combination with agents...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2705802/ https://www.ncbi.nlm.nih.gov/pubmed/19606213 http://dx.doi.org/10.1371/journal.pone.0006257 |