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X Chromosome Inactivation and Xist Evolution in a Rodent Lacking LINE-1 Activity
Dosage compensation in eutherian mammals occurs by inactivation of one X chromosome in females. Silencing of that X chromosome is initiated by Xist, a large non-coding RNA, whose coating of the chromosome extends in cis from the X inactivation center. LINE-1 (L1) retrotransposons have been implicate...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
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Public Library of Science
2009
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2705805/ https://www.ncbi.nlm.nih.gov/pubmed/19603076 http://dx.doi.org/10.1371/journal.pone.0006252 |