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X Chromosome Inactivation and Xist Evolution in a Rodent Lacking LINE-1 Activity

Dosage compensation in eutherian mammals occurs by inactivation of one X chromosome in females. Silencing of that X chromosome is initiated by Xist, a large non-coding RNA, whose coating of the chromosome extends in cis from the X inactivation center. LINE-1 (L1) retrotransposons have been implicate...

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Detalles Bibliográficos
Autores principales: Cantrell, Michael A., Carstens, Bryan C., Wichman, Holly A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2705805/
https://www.ncbi.nlm.nih.gov/pubmed/19603076
http://dx.doi.org/10.1371/journal.pone.0006252