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The Nature of Increased Circulating CD4(+)CD25(-)Foxp3(+) T Cells in Patients with Systemic Lupus Erythematosus: A Novel Hypothesis

The forkhead family transcriptional factor (Foxp3) is an important lineage marker for regulatory T (Treg) cells. Foxp3 expression is primarily restricted to CD4+CD25+ cell population. Recently, an intriguing phenomenon is highlighted that there is a considerable amount of CD4(+)CD25(-)Foxp3(+) T cel...

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Detalles Bibliográficos
Autores principales: Yan, Bing, Liu, Yi
Formato: Texto
Lenguaje:English
Publicado: Bentham Open 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2705839/
https://www.ncbi.nlm.nih.gov/pubmed/19590592
http://dx.doi.org/10.2174/1874312900903010022