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Reactive oxygen species mediate TNFR1 increase after TRPV1 activation in mouse DRG neurons
BACKGROUND: Transient receptor potential vanilloid subtype 1 (TRPV1) is activated by low pH/protons and is well known to be involved in hyperalgesia during inflammation. Tumor necrosis factor α (TNF-α), a proinflammatory cytokine, is involved in nociceptive responses causing hyperalgesia through TNF...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2009
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2706230/ https://www.ncbi.nlm.nih.gov/pubmed/19531269 http://dx.doi.org/10.1186/1744-8069-5-31 |