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Reactive oxygen species mediate TNFR1 increase after TRPV1 activation in mouse DRG neurons

BACKGROUND: Transient receptor potential vanilloid subtype 1 (TRPV1) is activated by low pH/protons and is well known to be involved in hyperalgesia during inflammation. Tumor necrosis factor α (TNF-α), a proinflammatory cytokine, is involved in nociceptive responses causing hyperalgesia through TNF...

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Detalles Bibliográficos
Autores principales: Ma, Fei, Zhang, Liping, Westlund, Karin N
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2706230/
https://www.ncbi.nlm.nih.gov/pubmed/19531269
http://dx.doi.org/10.1186/1744-8069-5-31