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Interfering ribonucleic acids that suppress expression of multiple unrelated genes

BACKGROUND: Short interfering RNAs (siRNAs) have become the research tool of choice for gene suppression, with human clinical trials ongoing. The emphasis so far in siRNA therapeutics has been the design of one siRNA with complete complementarity to the intended target. However, there is a need for...

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Detalles Bibliográficos
Autores principales: Passioura, Toby, Gozar, Mary M, Goodchild, Amber, King, Andrew, Arndt, Greg M, Poidinger, Michael, Birkett, Donald J, Rivory, Laurent P
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2706242/
https://www.ncbi.nlm.nih.gov/pubmed/19531249
http://dx.doi.org/10.1186/1472-6750-9-57