Transcriptional Termination Enhances Protein Expression in Human Cells

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Transcriptional termination of mammalian RNA polymerase II (Pol II) requires a poly(A) (pA) signal and, often, a downstream terminator sequence. Termination is triggered following recognition of the pA signal by Pol II and subsequent pre-mRNA cleavage, which occurs either at the pA site or in transc...

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Detalles Bibliográficos
Autores principales: West, Steven, Proudfoot, Nicholas J.
Formato: Texto
Lenguaje:English
Publicado: Cell Press 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2706331/
https://www.ncbi.nlm.nih.gov/pubmed/19217409
http://dx.doi.org/10.1016/j.molcel.2009.01.008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2706331/
https://www.ncbi.nlm.nih.gov/pubmed/19217409
http://dx.doi.org/10.1016/j.molcel.2009.01.008

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