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Transcriptional Termination Enhances Protein Expression in Human Cells
Transcriptional termination of mammalian RNA polymerase II (Pol II) requires a poly(A) (pA) signal and, often, a downstream terminator sequence. Termination is triggered following recognition of the pA signal by Pol II and subsequent pre-mRNA cleavage, which occurs either at the pA site or in transc...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Cell Press
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2706331/ https://www.ncbi.nlm.nih.gov/pubmed/19217409 http://dx.doi.org/10.1016/j.molcel.2009.01.008 |