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A novel in vivo murine model of cartilage regeneration. Age and strain-dependent outcome after joint surface injury

OBJECTIVES: To generate and validate a murine model of joint surface repair following acute mechanical injury. METHODS: Full thickness defects were generated in the patellar groove of C57BL/6 and DBA/1 mice by microsurgery. Control knees were either sham-operated or non-operated. Outcome was evaluat...

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Detalles Bibliográficos
Autores principales: Eltawil, N.M., De Bari, C., Achan, P., Pitzalis, C., Dell'Accio, F.
Formato: Texto
Lenguaje:English
Publicado: W.B. Saunders For The Osteoarthritis Research Society 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2706394/
https://www.ncbi.nlm.nih.gov/pubmed/19070514
http://dx.doi.org/10.1016/j.joca.2008.11.003