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Bench-to-bedside review: Severe lactic acidosis in HIV patients treated with nucleoside analogue reverse transcriptase inhibitors

Nucleoside reverse transcriptase inhibitors (NRTIs) are effective antiretroviral therapy for the treatment of HIV-infected patients. NRTIs can induce mitochondrial impairment that leads to a number of adverse events, including symptomatic lactic acidosis. In the present review, we describe the under...

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Detalles Bibliográficos
Autores principales: Claessens, Yann-Erick, Chiche, Jean-Daniel, Mira, Jean-Paul, Cariou, Alain
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC270672/
https://www.ncbi.nlm.nih.gov/pubmed/12793872